Analytical solutions for 13C isotopomer analysis of complex metabolic conditions:: substrate oxidation, multiple pyruvate cycles, and gluconeogenesis

被引：43

作者：

Sherry, AD

Jeffrey, FMH

Malloy, CR

机构：

[1] Univ Texas, Dept Chem, Richardson, TX 75083 USA

[2] Univ Texas, SW Med Ctr, Dallas Vet Affairs Med Ctr,Dept Radiol, Mary Nell & Ralph B Rogers Magnet Resonance ctr, Dallas, TX 75216 USA

[3] Univ Texas, SW Med Ctr, Dallas Vet Affairs Med Ctr, Div Cardiol,Dept Internal Med, Dallas, TX 75390 USA

来源：

METABOLIC ENGINEERING | 2004年 / 6卷 / 01期

关键词：

D O I：

10.1016/j.ymben.2003.10.007

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：12 / 24

页数：13

共 43 条

[1] TRACING HEPATIC GLUCONEOGENESIS RELATIVE TO CITRIC-ACID CYCLE ACTIVITY IN-VITRO AND IN-VIVO - COMPARISONS IN THE USE OF [3-C-13]LACTATE, [2-C-13]ACETATE, AND ALPHA-KETO[3-C-13]ISOCAPROATE [J].

BEYLOT, M ;

SOLOVIEV, MV ;

DAVID, F ;

LANDAU, BR ;

BRUNENGRABER, H .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (04) :1509-1514

[2] Applications of mass isotopomer analysis to nutrition research [J].

Brunengraber, H ;

Kelleher, JK ;

DesRosiers, C .

ANNUAL REVIEW OF NUTRITION, 1997, 17 :559-596

[3] Quantification of gluconeogenesis in cirrhosis: Response to glucagon [J].

Bugianesi, E ;

Kalhan, S ;

Burkett, E ;

Marchesini, G ;

McCullough, A .

GASTROENTEROLOGY, 1998, 115 (06) :1530-1540

[4]

CHANCE EM, 1983, J BIOL CHEM, V258, P3785

[5] Quantifying gluconeogenesis during fasting [J].

Chandramouli, V ;

Ekberg, K ;

Schumann, WC ;

Kalhan, SC ;

Wahren, J ;

Landau, BR .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1997, 273 (06) :E1209-E1215

[6] Metabolic compartmentation of lactate in the glucose-perfused rat heart [J].

Chatham, JC ;

Forder, JR .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 1996, 270 (01) :H224-H229

[7]

COHEN SM, 1983, J BIOL CHEM, V258, P4294

[8] PYRUVATE-CARBOXYLASE AND PROPIONYL-COA CARBOXYLASE AS ANAPLEROTIC ENZYMES IN SKELETAL-MUSCLE MITOCHONDRIA [J].

DAVIS, EJ ;

SPYDEVOLD, O ;

BREMER, J .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1980, 110 (01) :255-262

[9]

DIDONATO L, 1993, J BIOL CHEM, V268, P4170

[10] Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM [J].

Diraison, F ;

Large, V ;

Brunengraber, H ;

Beylot, M .

DIABETOLOGIA, 1998, 41 (02) :212-220

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