PET scans in radiotherapy planning of lung cancer

被引:70
作者
De Ruysscher, Dirk [1 ]
Nestle, Ursula [2 ]
Jeraj, Robert [3 ,4 ,5 ,6 ]
MacManus, Michael [7 ]
机构
[1] Maastricht Univ, Med Ctr, Dept Radiat Oncol, GROW Sch Oncol & Dev Biol,MAASTRO Clin, Maastricht, Netherlands
[2] Univ Hosp, Dept Radiat Oncol, Freiburg, Germany
[3] Univ Wisconsin, Dept Med Phys, Madison, WI 53706 USA
[4] Univ Wisconsin, Dept Human Oncol, Madison, WI USA
[5] Univ Wisconsin, Dept Radiol, Madison, WI 53706 USA
[6] Univ Wisconsin, Dept Biomed Engn, Madison, WI USA
[7] Peter MacCallum Canc Ctr, Dept Radiat Oncol, Melbourne, Vic, Australia
关键词
PET; Radiotherapy; Lung cancer; Planning; Delineation; POSITRON-EMISSION-TOMOGRAPHY; TARGET VOLUME DEFINITION; FDG-PET; RADICAL RADIOTHERAPY; NODE IRRADIATION; DOSE-ESCALATION; PRIMARY TUMOR; LYMPH-NODES; HIGH-IMPACT; CT;
D O I
10.1016/j.lungcan.2011.07.018
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Accurate delineation of the primary tumor and of involved lymph nodes is a key requisite for successful curative radiotherapy in non-small cell lung cancer (NSCLC). In recent years, it has become clear that the incorporation of FDG PET-CT scan information into the related processes of patient selection and radiotherapy planning has lead to significant improvements for patients with NSCLC. The use of FDG PET-CT information in radiotherapy planning allows better target volume definition, reduces inter-observer variability and encourages selective irradiation of involved mediastinal lymph nodes. PET-CT also opens the door for innovative radiotherapy delivery and the development of new concepts. However, care must be taken to avoid a variety of technical pitfalls and specific education is necessary, for clinicians and physicists alike. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:141 / 145
页数:5
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