IBD Of mice and men-shedding new light on IL-13 activity in IBD

被引：10

作者：

Danese, Silvio ^{[1
]}

机构：

[1] IRCCS Humanitas, IBD Ctr, I-20089 Milan, Italy

来源：

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2011年 / 8卷 / 03期

关键词：

NK-T-CELLS; ULCERATIVE-COLITIS;

D O I：

10.1038/nrgastro.2011.17

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A recent study in a mouse model of colitis has demonstrated that interleukin (IL)-13, through inhibition of the mixed type 1 and type 17 T-helper cell inflammatory response, has a protective effect. the decoy receptor Il-13R alpha 2 inhibits this protective effect, suggesting blockade of IL-13R alpha 2 as a potential therapy for patients with IBD.

引用

收藏

页码：128 / +

页数：2

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