Update on Human Immunodeficiency Virus (HIV)-2 Infection

被引:159
作者
Campbell-Yesufu, Omobolaji T.
Gandhi, Rajesh T. [1 ,2 ]
机构
[1] MIT, Massachusetts Gen Hosp, Ragon Inst, Boston, MA 02114 USA
[2] Harvard Univ, Boston, MA 02115 USA
关键词
PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; TO-CHILD TRANSMISSION; PLASMA VIRAL LOAD; HIV-2; INFECTION; ANTIRETROVIRAL THERAPY; DRUG-RESISTANCE; GUINEA-BISSAU; PHENOTYPIC SUSCEPTIBILITY; HIV-2-INFECTED PATIENTS; INTEGRASE INHIBITORS;
D O I
10.1093/cid/ciq248
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
Infection with human immunodeficiency virus type 2 (HIV-2) occurs mainly in West Africa, but an increasing number of cases have been recognized in Europe, India, and the United States. In this era of global integration, clinicians must be aware of when to consider the diagnosis of HIV-2 infection and how to test for this virus. Although there is debate regarding when therapy should be initiated and which regimen should be chosen, recent trials have provided important information on treatment options for HIV-2 infection. In this review, we present information on recent clinical advances in our understanding of HIV-2 infection and highlight remaining diagnostic and therapeutic challenges.
引用
收藏
页码:780 / 787
页数:8
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