The integration of microarray information in the drug development process

被引：44

作者：

Braxton, S ^{[1
]}

Bedilion, T ^{[1
]}

机构：

[1] Synteni Inc, Fremont, CA 94555 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1998年 / 9卷 / 06期

关键词：

D O I：

10.1016/S0958-1669(98)80144-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In the past year, microarray technologies have moved beyond the proof-of-principle stage. Microarrays are now being used for genome-wide expression monitoring, large-scale polymorphism screening and mapping, and for the evaluation of drug candidates.

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页码：643 / 649

页数：7

相关论文

共 38 条

[1] Accessing genetic information with high-density DNA arrays [J].

Chee, M ;

Yang, R ;

Hubbell, E ;

Berno, A ;

Huang, XC ;

Stern, D ;

Winkler, J ;

Lockhart, DJ ;

Morris, MS ;

Fodor, SPA .

SCIENCE, 1996, 274 (5287) :610-614

[2] Genomic mismatch scanning identifies human genomic DNA shared identical by descent [J].

Cheung, VG ;

Nelson, SF .

GENOMICS, 1998, 47 (01) :1-6

[3] Linkage-disequilibrium mapping without genotyping [J].

Cheung, VG ;

Gregg, JP ;

Gogolin-Ewens, KJ ;

Bandong, J ;

Stanley, CA ;

Baker, L ;

Higgins, MJ ;

Nowak, NJ ;

Shows, TB ;

Ewens, WJ ;

Spielman, RS .

NATURE GENETICS, 1998, 18 (03) :225-230

[4]

Cronin MT, 1996, HUM MUTAT, V7, P244, DOI 10.1002/(SICI)1098-1004(1996)7:3<244::AID-HUMU9>3.3.CO

[5]

2-D

[6]

DeRisi J, 1996, NAT GENET, V14, P457

[7] Exploring the metabolic and genetic control of gene expression on a genomic scale [J].

DeRisi, JL ;

Iyer, VR ;

Brown, PO .

SCIENCE, 1997, 278 (5338) :680-686

[8] A COMPARISON OF LINKAGE DISEQUILIBRIUM MEASURES FOR FINE-SCALE MAPPING [J].

DEVLIN, B ;

RISCH, N .

GENOMICS, 1995, 29 (02) :311-322

[9]

DUPUIS J, 1995, GENETICS, V140, P843

[10]

FEINGOLD E, 1993, AM J HUM GENET, V53, P234

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