A convenient procedure for palladium catalyzed cyanation using a unique bidentate phosphorus ligand

被引：91

作者：

Jensen, RS

Gajare, AS

Toyota, K

Yoshifuji, M

Ozawa, F

机构：

[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Aoba Ku, Sendai, Miyagi 9808578, Japan

[2] Kyoto Univ, Inst Chem Res, Res Ctr Elements Sci, Uji, Kyoto 6110011, Japan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 50期

基金：

日本学术振兴会;

关键词：

catalytic cyanation; aryl bromide; zinc cyanide; palladium catalyst; low-coordinated phosphorus ligand;

D O I：

10.1016/j.tetlet.2005.10.052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium complex bearing 1,2-diphenyl-3,4-diphosphinidenecyclobutene ligand (DPCB) has been used to facilitate the catalytic cyanation of aryl bromides. A series of substituted benzonitriles was prepared in good to high yields by the treatment of the corresponding aryl bromides with Zn(CN)(2) in N-methyl-2-pyrrolidone in the presence of 2-4 mol % catalyst at 100 degrees C for 16 h. (c) 2005 Elsevier Ltd. All rights reserved.

引用

收藏

页码：8645 / 8647

页数：3

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