Cold-induced metabolism

被引:31
作者
Lichtenbelt, WDV
Dannen, HAM
机构
[1] Maastricht Univ, Dept Human Biol, NL-6200 MD Maastricht, Netherlands
[2] THO Human Factors, Soesterberg, Netherlands
关键词
adaptive thermogenesis; nonshivering thermogenesis; cold response; energy expenditure; uncoupling proteins; brown adipose tissue;
D O I
10.1097/01.mco.0000078992.96795.5f
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The implications of the observed large individual variation in cold response is that a low metabolic response to cold can partly explain increased risk to develop obesity. Both the effect of environmental factors and genetic factors on nonshivering thermogenesis require more well controlled studies. With extended knowledge on these factors it can be ascertained if a pharmacological regimen is possible which would mimic the effects of chronic cold or elevated catecholamine levels, without attendant side effects.
引用
收藏
页码:469 / 475
页数:7
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