Phytocystatins and their target enzymes: From molecular biology to practical application: A review

被引:8
作者
Arai, S
Matsumoto, I
Abe, K
机构
[1] Tokyo Univ Agr, Fac Agr, Dept Nutr, Setagaya Ku, Tokyo 156, Japan
[2] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Bunkyo Ku, Tokyo 113, Japan
关键词
D O I
10.1111/j.1745-4514.1998.tb00245.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cystatins are protein inhibitors of cysteine proteinases. Oryzacystatin I (OC-I) has been cloned and is apparently the first well-defined cystatin of plant origin (phytocystatin). Besides OC-I, various other phytocystatins occur in rice, corn, wheat and soybean. Phytocystatins have endogenous target enzymes whose expression is induced by gibberellin, and also exogenous target enzymes from viruses and insects. It is thus likely that phytocystatins are involved in the regulation of intracellular protein catabolism as well as in the defense from infection. Better understanding of this phenomenon and cloning of appropriate genes will facilitate the creation of transgenic crops with enhanced resistance to viruses and insects.
引用
收藏
页码:287 / 299
页数:13
相关论文
共 34 条
[1]  
ABE K, 1988, J BIOL CHEM, V263, P7655
[2]  
ABE K, 1991, BIOMED BIOCHIM ACTA, V50, P637
[3]  
ABE K, 1987, AGR BIOL CHEM TOKYO, V51, P2763
[4]  
ABE K, 1987, J BIOL CHEM, V262, P16793
[5]   CORN KERNEL CYSTEINE PROTEINASE-INHIBITOR AS A NOVEL CYSTATIN SUPERFAMILY MEMBER OF PLANT-ORIGIN - MOLECULAR-CLONING AND EXPRESSION STUDIES [J].
ABE, M ;
ABE, K ;
KURODA, M ;
ARAI, S .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 209 (03) :933-937
[6]   ANTIVIRAL EFFECT OF ORYZACYSTATIN, A PROTEINASE-INHIBITOR IN RICE, AGAINST HERPES-SIMPLEX VIRUS TYPE-1 IN-VITRO AND IN-VIVO [J].
AOKI, H ;
AKAIKE, T ;
ABE, K ;
KURODA, M ;
ARAI, S ;
OKAMURA, RI ;
NEGI, A ;
MAEDA, H .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (04) :846-849
[7]  
Applebaum S.W., 1985, P279
[8]  
ARAI S, 1991, J BIOCHEM, V109, P294
[9]  
Arai S, 1995, ACS SYM SER, V605, P124
[10]  
Arai S., 1991, FOOD ENZYMOLOGY, V2, P83