An expeditious procedure for the isolation of ingenol from the seeds of Euphorbia lathyris

被引：77

作者：

Appendino, G

Tron, GC

Cravotto, G

Palmisano, G

Jakupovic, J

机构：

[1] Dipartimento Sci & Tecnol Farmaco, I-10125 Turin, Italy

[2] Tech Univ Berlin, Inst Organ Chem, D-10623 Berlin, Germany

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 01期

关键词：

D O I：

10.1021/np980218n

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A short and practical process for the isolation of ingenol (la) from an agricultural commodity (the seeds of Euphorbia lathyris) is described. Macrocyclic diterpene esters are obtained as byproducts, and the esterification pattern of the Euphorbia factors L-2 (3), L-3 (4b), and L-8 (4b) was established by 2D NMR measurements. Full spectroscopic data for these compounds are reported.

引用

页码：76 / 79

页数：4

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