Chronic myelogenous leukemia following kidney transplantation in a pediatric patient

被引：10

作者：

Mignozzi, M ^{[1
]}

Picca, S ^{[1
]}

机构：

[1] Bambino Gesu Childrens Hosp & Res Inst, Div Nephrol & Dialysis, I-00165 Rome, Italy

来源：

PEDIATRIC NEPHROLOGY | 2001年 / 16卷 / 11期

关键词：

chronic myelogenous leukemia; pediatric kidney transplantation; azathioprine; growth hormone;

D O I：

10.1007/s004670100667

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The incidence of cancer is increased following kidney transplantation. Chronic myelogenous leukemia (CML) has been previously reported in ten adult patients and only one pediatric patient post kidney transplantation. We report one male patient aged 18.8 years, on chronic dialysis from the age of 2 years, who was transplanted from a cadaver donor at the age of 8 years. He was treated with recombinant human growth hormone (rhGH) before transplantation and with azathioprine after kidney transplantation. Eight years after transplantation, CML was diagnosed and he was successfully treated with hydroxyurea and alpha -interferon. The follow-up is 28 months. The possible role of the combined action of rhGH and azathioprine in CML genesis is discussed.

引用

页码：852 / 853

页数：2

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