Prolactogenic effects of risperidone in male patients - a preliminary study

被引:40
作者
Shiwach, RS
Carmody, TJ
机构
[1] Univ Texas, SW Med Ctr, Dept Psychiat, Dallas, TX 75235 USA
[2] Univ Texas, SW Med Ctr, Acad Comp Serv, Dallas, TX USA
关键词
prolactin; dopamine; risperidone; testosterone;
D O I
10.1111/j.1600-0447.1998.tb10046.x
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
This preliminary study describes a case of a male patient who developed gynaecomastia and sexual difficulties whilst taking risperidone for chronic paranoid schizophrenia. Laboratory tests showed raised prolactin levels and depressed testosterone levels which were reversed on cessation of medication. A small study was subsequently conducted on male psychotic patients to compare the prolactogenic effects of risperidone (n=14) with traditional antipsychotic medication (n=15). The results showed a greater but non-significant prolactogenic effect of risperidone.
引用
收藏
页码:81 / 83
页数:3
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