Further experience with gastric stimulation to treat drug refractory gastroparesis

被引:78
作者
Forster, J
Sarosiek, I
Lin, Z
Durham, S
Denton, S
Roeser, K
McCallum, RW
机构
[1] Univ Kansas, Med Ctr, Dept Surg, Kansas City, KS 66160 USA
[2] Univ Kansas, Med Ctr, Dept Med, Kansas City, KS 66160 USA
关键词
gastroparesis; gastric electrical stimulation; gastric motility; quality of life; gastric emptying;
D O I
10.1016/j.amjsurg.2003.08.024
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Gastric electrical stimulation (GES) has been introduced for patients with gastroparesis refractory to pharmacological therapy. Methods: From April 1998 until November 2001, 55 patients underwent GES implantation at Kansas University Medical Center. All patients had prolonged gastric retention of a solid meal by scintigraphy at baseline. The etiologies were diabetes mellitus in 39, related to previous surgery in 9, and idiopathic in 7. Symptoms were graded using a 5-point scale and quality of fife was assessed with the SF-36 questionnaire. Body mass index and nutritional parameters were monitored. Hemoglobin A1C was measured in the diabetic patients. Results: Total symptom scores and the physical and mental composite scores of quality of life improved significantly. On average, gastric emptying did not change. Body mass index and body weight increased significantly. And days spent in hospital admissions were significantly decreased. At 1 year, diabetic patients experienced reduced hemoglobin A1C. Four devices were removed. One patient died of a pulmonary embolus postoperatively. Conclusions: In a large series of patients with gastroparesis, GES significantly improved symptoms and quality of life. (C) 2003 Excerpta Medica. Inc. All rights reserved.
引用
收藏
页码:690 / 695
页数:6
相关论文
共 19 条
[1]   Gastric electrical stimulation for medically refractory gastroparesis [J].
Abell, T ;
McCallum, R ;
Hocking, M ;
Koch, K ;
Abrahamsson, H ;
LeBlanc, I ;
Lindberg, G ;
Konturek, J ;
Nowak, T ;
Quigley, EMM ;
Tougas, G ;
Starkebaum, W .
GASTROENTEROLOGY, 2003, 125 (02) :421-428
[2]  
Al-Juburi A, 2001, GASTROENTEROLOGY, V120, pA647
[3]  
ALJUBURI A, 2002, NEUROGASTROENT MOTIL, V14, P432
[4]  
Bityutskiy LP, 1997, AM J GASTROENTEROL, V92, P1501
[5]   Delayed gastric emptying and gastric autommunity in type 1 diabetes [J].
De Block, CEM ;
De Leeuw, IH ;
Pelckmans, PA ;
Callens, D ;
Máday, E ;
Van Gaal, LF .
DIABETES CARE, 2002, 25 (05) :912-917
[6]  
Eckhauser FE, 1998, AM SURGEON, V64, P711
[7]   Novel surgical treatment and gastric pathology in diabetic gastroparesis [J].
Ejskjaer, NT ;
Bradley, JL ;
Buxton-Thomas, MS ;
Edmonds, ME ;
Howard, ER ;
Purewal, T ;
Thomas, PK ;
Watkins, PJ .
DIABETIC MEDICINE, 1999, 16 (06) :488-495
[8]   Gastric pacing is a new surgical treatment for gastroparesis [J].
Forster, J ;
Sarosiek, I ;
Delcore, R ;
Lin, Z ;
Raju, GS ;
McCallum, RW .
AMERICAN JOURNAL OF SURGERY, 2001, 182 (06) :676-681
[9]   Near-total completion gastrectomy for severe postvagotomy gastric stasis: Analysis of early and long-term results in 62 patients [J].
Forstner-Barthell, AW ;
Murr, MM ;
Nitecki, S ;
Camilleri, M ;
Prather, CM ;
Kelly, KA ;
Sarr, MG .
JOURNAL OF GASTROINTESTINAL SURGERY, 1999, 3 (01) :15-21
[10]   The diagnosis and work-up of the patient with gastroparesis [J].
Hornbuckle, K ;
Barnett, JL .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2000, 30 (02) :117-124