Is progressive osteoarthritis an atheromatous vascular disease?

被引：145

作者：

Conaghan, PG

Vanharanta, H

Dieppe, PA

机构：

[1] Univ Leeds, Acad Unit Musculoskeletal Dis, Leeds, W Yorkshire, England

[2] Leeds Musculoskeletal Serv, Leeds, W Yorkshire, England

[3] Univ Bristol, MRC, Hlth Serv Res Collaborat, Bristol, Avon, England

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2005年 / 64卷 / 11期

关键词：

D O I：

10.1136/ard.2005.039263

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Growing evidence from epidemiological studies suggests that osteoarthritis (OA) is linked to atheromatous vascular disease. This hypothesis article proposes that OA, or at least OA structural progression, may be an atheromatous vascular disease of subchondral bone. Further epidemiological studies, imaging investigations of relevant blood vessels, and trials of the effects of statins on the prevention and treatment of OA are needed to examine this hypothesis.

引用

页码：1539 / 1541

页数：3

共 37 条

[1]

ARNOLDI CC, 1994, ACTA ORTHOP SCAND, V65, P5

[2] Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism [J].

Aspden, RM ;

Scheven, BAA ;

Hutchison, JD .

LANCET, 2001, 357 (9262) :1118-1120

[3]

Beattie MS, 2005, J RHEUMATOL, V32, P106

[4]

BERGMAN AG, 1994, SKELETAL RADIOL, V23, P445

[5]

Burr DB, 2004, J RHEUMATOL, V31, P77

[6] DECREASED SURVIVAL WITH INCREASING PREVALENCE OF FULL-BODY, RADIOGRAPHICALLY DEFINED OSTEOARTHRITIS IN WOMEN [J].

CERHAN, JR ;

WALLACE, RB ;

ELKHOURY, GY ;

MOORE, TE ;

LONG, CR .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1995, 141 (03) :225-234

[7]

Collins D., 1949, PATHOLOGY ARTICULAR

[8]

Cooper C, 2000, ARTHRITIS RHEUM, V43, P995, DOI 10.1002/1529-0131(200005)43:5<995::AID-ANR6>3.0.CO

[9]

2-1

[10] Osteoarthritis: time to shift the paradigm [J].

Dieppe, P .

BMJ-BRITISH MEDICAL JOURNAL, 1999, 318 (7194) :1299-1300

← 1 2 3 4 →