Meta-analysis of functional outcome in Parkinson patients treated with unilateral pallidotomy

被引：2

作者：

Ahmad, SO

Mu, KL

Scott, SA

机构：

[1] Creighton Univ, Sch Pharm & Allied Hlth Profess, Dept Occupat Therapy, Omaha, NE 68178 USA

[2] Creighton Univ, Sch Pharm & Allied Hlth Profess, Dept Phys Therapy, Omaha, NE 68178 USA

来源：

NEUROSCIENCE LETTERS | 2001年 / 312卷 / 03期

关键词：

Parkinson's disease; meta-analysis; unilateral pallidotomy; functional outcome; activities of daily living;

D O I：

10.1016/S0304-3940(01)02218-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Parkinson's disease (PD) profoundly affects activities of daily living (ADL) and quality of human life. Although unilateral pallidotomy has become a common surgical treatment for persons with advanced PD, functional outcome data from previous reports have failed to uniformly support this procedure. In the present investigation, results from 12 studies meeting specific inclusion criteria were subjected to meta-analysis. Only reports featuring unilateral pallidotomy as the exclusive surgery, a sample size of at least five patients, explicit assessment of ADL, and sufficient quantitative data were subjected to analysis. Type of research design was not a factor in the selection process. The results of our analysis suggest that unilateral pallidotomy successfully enhances functional outcome in patients with clinically advanced PD. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：153 / 156

页数：4

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