Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films

被引：129

作者：

Sinani, VA

Koktysh, DS

Yun, BG

Matts, RL

Pappas, TC

Motamedi, M

Thomas, SN

Kotov, NA ^{[1
]}

机构：

[1] Oklahoma State Univ, Dept Chem, Stillwater, OK 74078 USA

[2] Oklahoma State Univ, Dept Biochem & Mol Biol, Stillwater, OK 74078 USA

[3] Univ Texas, Med Branch, Ctr Biomed Engn, Galveston, TX 77550 USA

来源：

NANO LETTERS | 2003年 / 3卷 / 09期

关键词：

D O I：

10.1021/nl0255045

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanostructured thin films fabricated from semiconductor nanoparticles (NPs) are of great interest for biomedical applications, but NP materials based on heavy metals can be cytotoxic. In this work, the preparation of semiconductor NPs followed the protocol of layer-by-layer (LBL) assembly, which alleviates this problem. Collagen/poly(acrylic acid) bilayers were added to CdTe/polycation LBL films to produce porous collagen bilayers. Such stratified multilayer systems showed successful cell attachment and survival while native NP films were strongly cytotoxic.

引用

页码：1177 / 1182

页数：6

共 74 条

[1] Aliev FG, 1999, ADV MATER, V11, P1006, DOI 10.1002/(SICI)1521-4095(199908)11:12<1006::AID-ADMA1006>3.0.CO
[2] 2-2
[3] Rationalizing the design of polymeric biomaterials
Angelova, N
Hunkeler, D
[J]. TRENDS IN BIOTECHNOLOGY, 1999, 17 (10) : 409 - 421
[4] Ultrathin films of inorganic materials (SiO2 nanoparticle, montmorillonite microplate, and molybdenum oxide) prepared by alternate layer-by-layer assembly with organic polyions
Ariga, K
Lvov, Y
Ichinose, I
Kunitake, T
[J]. APPLIED CLAY SCIENCE, 1999, 15 (1-2) : 137 - 152
[5] Optical fiber nanometer-scale Fabry-Perot interferometer formed by the ionic self-assembly monolayer process
Arregui, FJ
Matias, IR
Liu, YJ
Lenahan, KM
Claus, RO
[J]. OPTICS LETTERS, 1999, 24 (09) : 596 - 598
[6] BERG MC, 2003, POLYM MAT SCI ENG, V88, P46
[7] Bian SP, 2000, ADV MATER, V12, P1202, DOI 10.1002/1521-4095(200008)12:16<1202::AID-ADMA1202>3.0.CO
[8] 2-C
[9] Semiconductor nanocrystals as fluorescent biological labels
Bruchez, M
Moronne, M
Gin, P
Weiss, S
Alivisatos, AP
[J]. SCIENCE, 1998, 281 (5385) : 2013 - 2016
[10] Caruso F, 1999, ADV MATER, V11, P950

← 1 2 3 4 5 6 7 8 →