Precision Medicine - Personalized, Problematic, and Promising

被引：728

作者：

Jameson, J. Larry ^{[1
]}

Longo, Dan L. ^{[1
]}

机构：

[1] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2015年 / 372卷 / 23期

关键词：

CLINICAL-PRACTICE; THERAPY; INHIBITION; BIOMARKER; LYMPHOMA; EFFICACY; MUTATION; FUTURE; CANCER; SAFETY;

D O I：

10.1056/NEJMsb1503104

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：2229 / 2234

页数：6

共 35 条

[1]

[Anonymous], 2011, PREC MED BUILD KNOWL

[2] Automated Hovering in Health Care - Watching Over the 5000 Hours [J].

Asch, David A. ;

Muller, Ralph W. ;

Volpp, Kevin G. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (01) :1-3

[3] The microbiome revolution [J].

Blaser, Martin J. .

JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (10) :4162-4165

[4] Human laminopathies: nuclei gone genetically awry [J].

Capell, Brian C. ;

Collins, Francis S. .

NATURE REVIEWS GENETICS, 2006, 7 (12) :940-952

[5] Incorporation of Pharmacogenomics into Routine Clinical Practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline Development Process [J].

Caudle, Kelly E. ;

Klein, Teri E. ;

Hoffman, James M. ;

Mueller, Daniel J. ;

Whirl-Carrillo, Michelle ;

Gong, Li ;

McDonagh, Ellen M. ;

Sangkuhl, Katrin ;

Thorn, Caroline F. ;

Schwab, Matthias ;

Agundez, Jose A. G. ;

Freimuth, Robert R. ;

Huser, Vojtech ;

Lee, Ming Ta Michael ;

Iwuchukwu, Otito F. ;

Crews, Kristine R. ;

Scott, Stuart A. ;

Wadelius, Mia ;

Swen, Jesse J. ;

Tyndale, Rachel F. ;

Stein, C. Michael ;

Roden, Dan ;

Relling, Mary V. ;

Williams, Marc S. ;

Johnson, Samuel G. .

CURRENT DRUG METABOLISM, 2014, 15 (02) :209-217

[6] MEDICAL PROGRESS Acute HIV-1 Infection [J].

Cohen, Myron S. ;

Shaw, George M. ;

McMichael, Andrew J. ;

Haynes, Barton F. .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (20) :1943-1954

[7] A New Initiative on Precision Medicine [J].

Collins, Francis S. ;

Varmus, Harold .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (09) :793-795

[8] Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer [J].

Dawson, Sarah-Jane ;

Tsui, Dana W. Y. ;

Murtaza, Muhammed ;

Biggs, Heather ;

Rueda, Oscar M. ;

Chin, Suet-Feung ;

Dunning, Mark J. ;

Gale, Davina ;

Forshew, Tim ;

Mahler-Araujo, Betania ;

Rajan, Sabrina ;

Humphray, Sean ;

Becq, Jennifer ;

Halsall, David ;

Wallis, Matthew ;

Bentley, David ;

Caldas, Carlos ;

Rosenfeld, Nitzan .

NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (13) :1199-1209

[9] Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia [J].

Druker, Brian J. ;

Guilhot, Francois ;

O'Brien, Stephen G. ;

Gathmann, Insa ;

Kantarjian, Hagop ;

Gattermann, Norbert ;

Deininger, Michael W. N. ;

Silver, Richard T. ;

Goldman, John M. ;

Stone, Richard M. ;

Cervantes, Francisco ;

Hochhaus, Andreas ;

Powell, Bayard L. ;

Gabrilove, Janice L. ;

Rousselot, Philippe ;

Reiffers, Josy ;

Cornelissen, Jan J. ;

Hughes, Timothy ;

Agis, Hermine ;

Fischer, Thomas ;

Verhoef, Gregor ;

Shepherd, John ;

Saglio, Giuseppe ;

Gratwohl, Alois ;

Nielsen, Johan L. ;

Radich, Jerald P. ;

Simonsson, Bengt ;

Taylor, Kerry ;

Baccarani, Michele ;

So, Charlene ;

Letvak, Laurie ;

Larson, Richard A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (23) :2408-2417

[10] The role of FDG-PET in defining prognosis of Hodgkin lymphoma for early-stage disease [J].

Evens, Andrew M. ;

Kostakoglu, Lale .

BLOOD, 2014, 124 (23) :3356-3364

← 1 2 3 4 →