Treatment of Absidia corymbifera infection in mice with amphotericin B and itraconazole

被引：18

作者：

Mosquera, J

Warn, PA

Rodriguez-Tudela, JL

Denning, DW ^{[1
]}

机构：

[1] Univ Manchester, Hope Hosp, Sch Med, Infect Dis Sect, Salford M6 8HD, Lancs, England

[2] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Micol, Madrid 28220, Spain

[3] N Manchester Grp Hosp, Dept Trop Med & Infect Dis, Manchester M8 6RB, Lancs, England

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2001年 / 48卷 / 04期

关键词：

D O I：

10.1093/jac/48.4.583

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The activities of amphotericin B and itraconazole were studied in a temporarily neutropenic murine model of disseminated Absidia corymbifera infection, caused by two different strains. Amphotericin B MICs were 0.25 mg/L for both strains and itraconazole MICs were 1 and 2 mg/L. Amphotericin B was effective in vivo with both isolates. Itraconazole was less effective.

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页码：583 / 586

页数：4

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