Sch 65676: A novel fungal metabolite with the inhibitory activity against the cytomegalovirus protease

被引：14

作者：

Chu, M

Mierzwa, R

Truumees, I

King, A

Patel, M

Pichardo, J

Hart, A

Dasmahapatra, B

Das, PR

Puar, MS

机构：

[1] Schering-Plough Research Institute, Kenilworth, NJ 07003

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 23期

关键词：

D O I：

10.1016/0040-4039(96)00748-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new secondary metabolite, Sch 65676 (1), was isolated from the fermentation broth of a fungal culture. The structure of 1 was elucidated based on comprehensive NMR studies including COSY, NOE and HMBC experiments. Compound 1 displays inhibitory activity against the cytomegalovirus (CMV) protease. (C) 1996 Elsevier Science Ltd

引用

页码：3943 / 3946

页数：4

共 7 条

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