Lovastatin plus probucol for prevention of restenosis after percutaneous transluminal coronary angioplasty

被引：31

作者：

OKeefe, JH

Stone, GW

McCallister, BD

Maddex, C

Ligon, R

Kacich, RL

Kahn, J

Cavero, PG

Hartzler, GO

McCallister, BD

机构：

[1] ST LUKES HOSP,MID AMER HEART INST,KANSAS CITY,MO 64111

[2] CARDIOVASC INST,MT VIEW,CA

[3] MICHIGAN HEART PC,ANN ARBOR,MI

[4] UNIV CINCINNATI,CINCINNATI,OH

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1996年 / 77卷 / 08期

关键词：

D O I：

10.1016/S0002-9149(97)89325-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We hypothesized that combination therapy inc luding lovastatin (for low-density lipoprotein [LDL] lowering) and probucol (for antioxidant activity) may be useful in reducing or preventing restenosis and recurrent coronary events after percutaneous transluminal coronary angioplasty (PTCA). The Angioplasty Plus Probucol/Lovastatin Evaluation (APPLE) trial was designed to test this hypothesis.

引用

页码：649 / &

页数：5

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