The polyclonal origin of myocyte lineages

被引：42

作者：

Mikawa, T

Fischman, DA

机构：

[1] Dept. of Cell Biology and Anatomy, Cornell University, Medical College, New York, NY 10021

来源：

ANNUAL REVIEW OF PHYSIOLOGY | 1996年 / 58卷

关键词：

heart development; retrovirus; atrium; ventricle; Purkinje fiber;

D O I：

10.1146/annurev.ph.58.030196.002453

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The heart beat is coordinated by the integrated activities of three myocyte subpopulations: atrial myocytes, ventricular myocytes, and cells of the cardiac conduction system. In this review we discuss the classic fate map and recent retroviral cell lineage studies to better understand the origin, timing, and mechanisms regulating (a) the formation of these three myocyte lineages and (b) the morphogenetic plan underlying formation of the myocardial walls and the conduction system.

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页码：509 / 521

页数：13

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