Exercise-induced human coronary collateral function: Quantitative assessment during acute coronary occlusions

被引：10

作者：

Pohl, T ^{[1
]}

Wustmann, K ^{[1
]}

Zbinden, S ^{[1
]}

Windecker, S ^{[1
]}

Mehta, H ^{[1
]}

Meier, B ^{[1
]}

Seiler, C ^{[1
]}

机构：

[1] Univ Hosp Bern, Swiss Cardiovasc Ctr Bern, CH-3010 Bern, Switzerland

来源：

CARDIOLOGY | 2003年 / 100卷 / 02期

关键词：

coronary circulation; collateral circulation; exercise; coronary artery disease; pathophysiology;

D O I：

10.1159/000073039

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In 50 patients undergoing percutaneous transluminal coronary angioplasty because of chronic angina pectoris, a collateral flow index (CFI) was determined at the start and the end of two 1-min coronary occlusions, randomly accompanied by a resting state or a 3-min dynamic handgrip exercise (DHE). CFI expressing collateral flow relative to normal antegrade flow was determined by simultaneous coronary occlusive pressure, mean aortic pressure and central venous pressure measurements. When comparing CFI without and with DHE at the start as well as at the end of balloon occlusions, a significant increase was observed with DHE (overall p < 0.0001); start: 0.18 +/- 0.12 vs. 0.22 +/- 0.13, respectively (p = 0.01); end of occlusion: 0.21 +/- 0.14 vs. 0.25 +/- 0.14, respectively (p = 0.007). Copyright (C) 2003 S. Karger AG, Basel.

引用

页码：53 / 60

页数：8

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