Hospital-based study of the economic burden associated with rotavirus diarrhea in Hong kong

被引:29
作者
Nelson, EAS
Tam, JS
Yu, LM
Ng, YC
Bresee, JS
Poon, KH
Ng, CH
Ip, KS
Mast, TC
Chan, PKS
Parashar, UD
Fok, TF
Glass, RI
机构
[1] Chinese Univ Hong Kong, Dept Microbiol, Shatin, Hong Kong, Peoples R China
[2] Chinese Univ Hong Kong, Ctr Clin Trials & Epidemiol Res, Shatin, Hong Kong, Peoples R China
[3] Hong Kong Baptist Univ, Dept Econ, Hong Kong, Hong Kong, Peoples R China
[4] Tuen Mun Hosp, Dept Paediat & Adolescent Med, Tuen Mun, Hong Kong, Peoples R China
[5] Queen Elizabeth Hosp, Dept Paediat & Adolescent Med, Hong Kong, Hong Kong, Peoples R China
[6] Pamela Youde Nethersole Eastern Hosp, Dept Paediat & Adolescent Med, Hong Kong, Hong Kong, Peoples R China
[7] Ctr Dis Control & Prevent, Atlanta, GA USA
[8] Merck Res Labs, West Point, PA USA
关键词
D O I
10.1086/431493
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. Rotavirus infection is the most common cause of severe diarrhea in both developed and developing countries. Methods. To estimate the economic burden associated with rotavirus infection in Hong Kong, we combined data on the disease burden of rotavirus-associated hospital admissions with detailed cost data for a subsample of 471 children with diarrhea admitted to hospitals. Results. The annual total social cost and total direct medical cost for rotavirus-associated admissions were calculated as US $4.3 and US $4 million, respectively, by use of data collected during March 2001 to March 2003. The estimate of the direct medical costs was similar to 4-fold higher than a previous estimate; this difference largely reflects the greater disease burden identified through active disease surveillance conducted under the auspices of the Asian Rotavirus Surveillance Network. On average, families spent US $120 when their child's admission was associated with rotavirus infection; this cost represents similar to 10% of the monthly salary of an unskilled or service worker. Conclusions. These data emphasize the potential for a safe and effective rotavirus vaccine to reduce the economic burden associated with rotavirus disease.
引用
收藏
页码:S64 / S70
页数:7
相关论文
共 9 条
[1]  
[Anonymous], 1999, MMWR Recomm Rep, V48, P1
[2]   First report from the Asian rotavirus surveillance network [J].
Bresee, J ;
Fang, ZY ;
Wang, B ;
Nelson, EAS ;
Tam, J ;
Soenarto, Y ;
Wilopo, SA ;
Kilgore, P ;
Kim, JS ;
Kang, JO ;
Lan, WS ;
Gaik, CL ;
Moe, K ;
Chen, KT ;
Jiraphongsa, C ;
Pongsuwanna, Y ;
Van Man, N ;
Van Tu, P ;
Luan, LT ;
Hummelman, E ;
Gentsch, JR ;
Glass, R .
EMERGING INFECTIOUS DISEASES, 2004, 10 (06) :988-995
[3]   Current status and future priorities for rotavirus vaccine development, evaluation and implementation in developing countries [J].
Bresee, JS ;
Glass, RI ;
Ivanoff, B ;
Gentsch, JR .
VACCINE, 1999, 17 (18) :2207-2222
[4]   Rotavirus infection in Hong Kong: epidemiology and estimates of disease burden [J].
Chan, PKS ;
Tam, JS ;
Nelson, EAS ;
Fung, KSC ;
Adeyemi-Doro, FAB ;
Fok, TF ;
Cheng, AF .
EPIDEMIOLOGY AND INFECTION, 1998, 120 (03) :321-325
[5]   Influenza-related hospitalizations among children in Hong Kong [J].
Chiu, SS ;
Lau, YL ;
Chan, KH ;
Wong, WHS ;
Peiris, JSM .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (26) :2097-2103
[6]  
Efron B., 1994, INTRO BOOTSTRAP, DOI DOI 10.1201/9780429246593
[7]   Estimates of rotavirus disease burden in Hong Kong: Hospital-based surveillance [J].
Nelson, EAS ;
Tam, JS ;
Bresee, JS ;
Poon, KH ;
Ng, CH ;
Ip, KS ;
Mast, TC ;
Chan, PKS ;
Parashar, UD ;
Fok, TF ;
Glass, RI .
JOURNAL OF INFECTIOUS DISEASES, 2005, 192 :S71-S79
[8]  
SMITH JC, 1995, PEDIATRICS, V96, P609
[9]   Cost-effectiveness analysis of a rotavirus immunization program for the United States [J].
Tucker, AW ;
Haddix, AC ;
Bresee, JS ;
Holman, RC ;
Parashar, UD ;
Glass, RI .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (17) :1371-1376