A new bioactive norquinone-methide triterpene from Maytenus scutioides

被引：19

作者：

González, AG

Alvarenga, NL

Bazzocchi, IL ^{[1
]}

Ravelo, AG

Moujir, L

机构：

[1] Univ La Laguna, Inst Univ Bioorgan, E-38206 Tenerife, Spain

[2] Univ La Laguna, Dept Microbiol & Biol Celular, E-38206 Tenerife, Spain

来源：

PLANTA MEDICA | 1998年 / 64卷 / 08期

关键词：

D O I：

10.1055/s-2006-957581

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

By antimicrobial and cytotoxic-guided fractionation, a bioactive norquinone-methide triterpene, 15 alpha-hydroxypristimerin, was isolated from a South American medicinal plant, Maytenus scutioides. Its structure was determined on the basis of spectroscopic evidence. Successful chemical transformation of pristimerin to netzahualcoyene indicates that the 15-hydroxy compounds seems to be a possible precursor of 14(15)-ene-quinone-methide-triterpenoids in the biogenetic pathway.

引用

页码：769 / 771

页数：3

共 11 条

[1]

DIAS MN, 1990, J CHEM RES M, P1801

[2]

GONZALES AG, 1988, FARMACO, V43, P501

[3] NEW EPIMERIC DI-TRITERPENE QUINONE ETHERS - THEIR PARTIAL SYNTHESIS AND THAT OF NETZAHUALCOYENE FROM PRISTIMERIN AND DDQ [J].