Response to hepatitis A vaccine in HIV patients in the HAART era

被引：33

作者：

Rimland, D ^{[1
]}

Guest, JL ^{[1
]}

机构：

[1] Emory Univ, Sch Med, VA Med Ctr, Atlanta, GA 30322 USA

来源：

AIDS | 2005年 / 19卷 / 15期

关键词：

D O I：

10.1097/01.aids.0000186815.99993.55

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated the development of hepatitis A antibody after vaccination in a large cohort of patients studied in a clinical setting after the introduction of HAART. Overall, 130 of 214 vaccinated individuals developed hepatitis A antibody. In a multivariate analysis, only the CD4 cell count at the time of vaccination was associated with an absence of response. The lack of association with the nadir CD4 cell count suggests that patients will. respond to vaccine after immunological reconstitution in response to HAART.

引用

页码：1702 / 1704

页数：3

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