Incidence of aspirin nonresponsiveness using the Ultegra Rapid Platelet Function Assay-ASA

被引：107

作者：

Wang, JC

Aucoin-Barry, D

Manuelian, D

Monbouquette, R

Reisman, M

Gray, W

Block, PC

Block, EH

Ladenheim, M

Simon, DI

机构：

[1] Harvard Univ, Div Cardiovasc, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA

[2] Swedish Med Ctr, Seattle, WA USA

[3] Emory Univ Hosp, Div Cardiovasc, Atlanta, GA 30322 USA

[4] Providence St Joseph Med Ctr, Burbank, CA USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2003年 / 92卷 / 12期

关键词：

D O I：

10.1016/j.amjcard.2003.08.072

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the incidence of aspirin nonresponsiveness in a prospective, multicenter registry (n = 422 patients) to be 23% using the Ultegra Rapid Platelet Function Assay-ASA, and determined a history of coronary artery disease to be associated with twice the odds of being an aspirin nonresponder (odds ratio 2.01 95% confidence interval 1.189 to 3.411, p = 0.009). Further prospective studies are needed to correlate aspirin nonresponsiveness to adverse clinical events. (C) 2003 by Excerpta Medica, Inc.

引用

页码：1492 / 1494

页数：3

共 12 条

[1]

Baigent C, 2002, BMJ-BRIT MED J, V324, P71, DOI 10.1136/bmj.324.7329.71

[2] Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events [J].