A preparative scale reduction of alkyl disulfides with tributyl phosphine and water

被引：23

作者：

Ayers, JT ^{[1
]}

Anderson, SR ^{[1
]}

机构：

[1] Trinity Coll, Dept Chem, Hartford, CT 06106 USA

来源：

SYNTHETIC COMMUNICATIONS | 1999年 / 29卷 / 03期

关键词：

D O I：

10.1080/00397919908085777

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of alkyl disulfides has been shown to be reduced by tributyl phosphine at room temperature. The resulting thiols were then acylated in the same pot and isolated in good yields. This sequence is convenient and is a practical option for the preparation of gram quantities of thiol or thioester from the corresponding disulfide.

引用

页码：351 / 358

页数：8

共 20 条

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