Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp.

被引：138

作者：

Kaye, KS

Cosgrove, S

Harris, A

Eliopoulos, GM

Carmeli, Y

机构：

[1] Harvard Univ, Sch Med, Div Infect Dis, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02115 USA

[3] Univ Maryland, Div Healthcare Outcomes, Dept Epidemiol & Prevent Med, Baltimore, MD 21201 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 09期

关键词：

D O I：

10.1128/AAC.45.9.2628-2630.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Among 477 patients with susceptible Enterobacter spp., 49 subsequently harbored third-generation cephalosporin-resistant Enterobacter spp. Broad-spectrum cephalosporins were independent risk factors for resistance (relative risk [OR] = 2.3, P = 0.01); quinolone therapy was protective (OR = 0.4, P = 0.03). There were trends toward decreased risk for resistance among patients receiving broad-spectrum cephalosporins and either aminoglycosides or imipenem. Of the patients receiving broad-spectrum cephalosporins, 19% developed resistance.

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收藏

页码：2628 / 2630

页数：3

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