Preparation and characterization of a quaternary ammonium derivative of pectin

被引：103

作者：

Fan, Lihong ^{[1
]}

Cao, Mi ^{[1
]}

Gao, Song ^{[1
]}

Wang, Weiping ^{[2
]}

Peng, Kai ^{[1
]}

Tan, Chang ^{[1
]}

Wen, Feng ^{[1
]}

Tao, Shengxiang ^{[3
]}

Xie, Weiguo ^{[4
]}

机构：

[1] Wuhan Univ Technol, Coll Chem Engn, Wuhan 430070, Peoples R China

[2] Hubei Univ Technol, Coll Bioengn, Wuhan 430068, Peoples R China

[3] Wuhan Univ Technol, Zhongnan Hosp, Dept Orthoped, Wuhan 430070, Peoples R China

[4] 3rd Hosp Wuhan, Wuhan 430000, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2012年 / 88卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Pectin; Quaternization; Moisture absorption; Moisture retention; Antimicrobial activity; ANTIMICROBIAL ACTIVITY; KONJAC GLUCOMANNAN; CITRUS PECTIN; CHITOSAN; CELLULOSE; POLYSACCHARIDES; QUATERNIZATION; ESTERIFICATION; BEHAVIOR; STARCH;

D O I：

10.1016/j.carbpol.2012.01.021

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Cationic derivatives of pectin were prepared by reacting pectin with 3-chloro-2-hydroxypropyltrimethylammonium chloride (CHPTAC) in presence of sodium hydroxide (NaOH). The chemical structures of derivative were characterized by using elemental analysis, FT-IR, and C-13 NMR spectroscopy. The results revealed that the degree of substitution (DS) of quaternized pectin (QP) could be controlled by adjusting the molar ratio of CHPTAC to pectin, the molar ratio of NaOH to CHPTAC and reaction temperature occurred during quaternization. The moisture absorption (R-a) and moisture retention (R-h) abilities of QP are closely related to the DS value. With the DS value increasing, R-a and R-h increased. In vitro antimicrobial activity assessment exhibited QP showed pronounced inhibitory effect against the three bacteria (Staphylococcus aureus, Escherichia coli, and Bacillus subtilis). The improved functionalities of the derivative might be explained by its polycationic characteristics. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：707 / 712

页数：6

共 43 条

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Phosphated crosslinked pectin as a potential excipient for specific drug delivery: preparation and physicochemical characterization [J].