Optimization of thoracic spiral CT: Effects of iodinated contrast medium concentration

被引：42

作者：

Rubin, GD ^{[1
]}

Lane, MJ ^{[1
]}

Bloch, DA ^{[1
]}

Leung, AN ^{[1
]}

Stark, P ^{[1
]}

机构：

[1] STANFORD UNIV,SCH MED,DEPT BIOSTAT,STANFORD,CA 94305

来源：

RADIOLOGY | 1996年 / 201卷 / 03期

关键词：

arteries; CT; computed tomography (CT); artifact; contrast enhancement; veins;

D O I：

10.1148/radiology.201.3.8939232

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

PURPOSE: To determine the effect of varying iodine concentration on arterial enhancement and perivenous artifact during thoracic spiral computed tomographic (CT) scanning. MATERIALS AND METHODS: One hundred thirty-eight outpatients received 15.0 g (n = 76) or 22.5 g (n = 62) of iodine (300 mg/mL iodine) while undergoing thoracic spiral CT. Patients received either undiluted contrast medium, 1:1 normal saline dilution, or 3:1 normal saline dilution. Contrast medium was injected at a flow rate determined to deliver the entire iodine dose within 40 seconds. Attenuation was measured within arteries and veins. Three blinded thoracic radiologists independently graded perivenous artifact and arterial enhancement. RESULTS: Perivenous artifacts were statistically significantly reduced with successive iodine dilution (P < .002). Arterial enhancement was statistically significantly better with 15.0 g of iodine diluted 1:1 when compared with the same iodine dose undiluted or diluted 3:1 (P < .01). Arterial enhancement achieved with 15.0 g of iodine diluted 1:1 was not statistically significantly lower than that achieved with 22.5 g of iodine diluted 1:1 (P > .31); however, venous artifact was greater with 22.5 g of iodine (P < .004). CONCLUSION: Reduced iodine concentration appears to diminish perivenous artifact and to result in improved arterial enhancement during thoracic spiral CT.

引用

页码：785 / 791

页数：7

共 10 条

[1] SAMPLE-SIZE REQUIREMENTS AND THE COST OF A RANDOMIZED CLINICAL-TRIAL WITH REPEATED MEASUREMENTS [J].