Fatal acute granulomatous pulmonary aspergillosis in a healthy subject after inhalation of vegetal dust

被引：11

作者：

Batard, E

Renaudin, K

Morin, O

Desjars, P

Germaud, P ^{[1
]}

机构：

[1] CHU, Hop Laennec, Clin Pneumol, F-44800 St Herblain, France

[2] CHU Nantes, Serv Urgences, F-44035 Nantes 01, France

[3] CHU Nantes, Anat Pathol Lab, F-44035 Nantes 01, France

[4] CHU Nantes, Lab Parasitol Mycol, F-44035 Nantes 01, France

[5] CHU Nantes, Serv Reanimat Med Polyvalente, F-44035 Nantes 01, France

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2003年 / 22卷 / 06期

关键词：

D O I：

10.1007/s10096-003-0939-x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A previously healthy 28-year-old man presented a few hours after inhalation of vegetal dust with acute bilateral community-acquired pneumonia, which caused death in 10 days despite treatment with broad-spectrum antibiotics, intravenous amphotericin B, inotropic support, and mechanical ventilation. A postmortem lung biopsy indicated miliary granulomatous pulmonary aspergillosis. Six similar previously published cases of acute granulomatous pulmonary aspergillosis are reviewed. This entity in adulthood may reveal a defect in neutrophil or macrophage function, such as late-onset chronic granulomatous disease.

引用

页码：357 / 359

页数：3

共 13 条

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Chandler FW, 1994, Pulmonary pathology, P351

[2] MICROGRANULOMATOUS ASPERGILLOSIS AFTER SHOVELING WOOD CHIPS - REPORT OF A FATAL OUTCOME IN A PATIENT WITH CHRONIC GRANULOMATOUS-DISEASE [J].