Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan

被引：128

作者：

Turin, Tanvir Chowdhury ^{[1
]}

Kita, Yoshikuni ^{[1
]}

Rumana, Nahid ^{[1
]}

Takashima, Naoyuki ^{[1
,2
]}

Kadota, Aya ^{[1
]}

Matsui, Kenji ^{[3
]}

Sugihara, Hideki ^{[4
]}

Morita, Yutaka ^{[5
]}

Nakamura, Yasuyuki ^{[1
,6
]}

Miura, Katsuyuki ^{[1
]}

Ueshima, Hirotsugu ^{[1
,2
]}

机构：

[1] Shiga Univ Med Sci, Dept Hlth Sci, Otsu, Shiga 5202192, Japan

[2] Shiga Univ Med Sci, Lifestyle Related Dis Prevent Ctr, Otsu, Shiga 5202192, Japan

[3] Univ Tokyo, Ctr Biomed Eth & Law, Tokyo, Japan

[4] Takashima Gen Hosp, Dept Internal Med, Shiga, Japan

[5] Makino Hosp, Shiga, Japan

[6] Kyoto Womens Univ, Dept Cardiovasc Epidemiol, Kyoto, Japan

来源：

HYPERTENSION RESEARCH | 2010年 / 33卷 / 09期

关键词：

brachial-ankle pulse wave velocity; longitudinal cohort study; predictor of mortality; ARTERIAL STIFFNESS; CLINICAL-APPLICATIONS; INDEX;

D O I：

10.1038/hr.2010.103

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Brachial-ankle pulse wave velocity (baPWV) is a relatively new non-invasive measure of arterial stiffness obtained using an automated system. We assessed the relationship between baPWV and 6.5-year overall mortality from the Takashima cohort study. The baPWV was measured in 2642 participants at baseline. When participants were divided into tertiles, all-cause mortality increased significantly as baPWV increased (P<0.001). Participants in the highest baPWV tertile showed an increased risk of all-cause mortality evidenced by a multivariable adjusted hazard ratio of 6.8 (95% confidence interval: 1.4-32.8) as compared with the lowest tertile. The present study demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population. Hypertension Research (2010) 33, 922-925; doi: 10.1038/hr.2010.103; published online 17 June 2010

引用

页码：922 / 925

页数：4

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