Growth hormone therapy for short children born small for gestational age

被引：17

作者：

Chatelain, P. ^{[1
]}

Carrascosa, A.

Bona, G.

Ferrandez-Longas, A.

Sippell, W.

机构：

[1] Hop Debrousse, Serv Endocrinol& Diabetol Pediat, FR-69322 Lyon 05, France

[2] Hosp Materno Infantil Vall Hebron, Dept Pediat, Barcelona, Spain

[3] Univ Piemonte Orientale, Dept Med Sci, Pediat Unit, Novara, Italy

[4] Univ Childrens Hosp Miguel Servet, Endocrinol Unit, Zaragoza, Spain

[5] Univ Childrens Hosp, Div Endocrinol & Diabetol, Kiel, Germany

来源：

HORMONE RESEARCH | 2007年 / 68卷 / 06期

关键词：

recombinant human growth hormone therapy; safety considerations; growth hormone therapy; small-for-gestational-age children;

D O I：

10.1159/000107935

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Children born small for gestational age may demonstrate continued growth retardation, resulting in persistent short stature. In the majority of the cases, this is linked with abnormal growth hormone secretion and also abnormal insulin-like growth factor levels. This review discusses the treatment of such children with recombinant human growth hormone. It illustrates the importance of starting therapy early, the dose-dependent response, and the advantages of continuous therapy and describes safety considerations. Copyright (c) 2007 S. Karger AG, Basel.

引用

页码：300 / 309

页数：10

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