Selective detection of catecholamines by synthetic receptors embedded in chromatic polydiacetylene vesicles

被引：93

作者：

Kolusheva, S

Molt, O

Herm, M

Schrader, T ^{[1
]}

Jelinek, R

机构：

[1] Univ Marburg, Dept Chem, D-35032 Marburg, Germany

[2] Ben Gurion Univ Negev, Ilse Katz Ctr Nanotechnol, IL-84105 Beer Sheva, Israel

[3] Ben Gurion Univ Negev, Dept Chem, IL-84105 Beer Sheva, Israel

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 28期

关键词：

D O I：

10.1021/ja052436q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new detection scheme for catecholamines was constructed through embedding synthetic receptors within vesicles comprising phospholipids and polydiacetylene. Fluorescence emission of the polydiacetylene was induced through specific interactions between the soluble ligands and the vesicle-incorporated hosts. The system demonstrated remarkable selectivity among structurally similar ligands and achieved much lower detection thresholds compared to that of other reported catecholamine sensors. The chromatic assembly provides a generic route for high sensitivity detection of ligand-receptor interactions. Copyright © 2005 American Chemical Society.

引用

页码：10000 / 10001

页数：2

共 22 条

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