Development of a phase III trial of hematopoietic stem cell transplantation for systemic lupus erythematosus

被引:10
作者
Burt, RK
Marmont, A
Arnold, R
Heipe, F
Firestein, GS
Carrier, E
Hahn, B
Barr, W
Oyama, Y
Snowden, J
Kalunian, K
Traynor, A
机构
[1] Osped San Martino Genova, Ctr Trapianti Midollo Osseo, Genoa, Italy
[2] Univ Klinikum Campus Charite Mitte, Berlin, Germany
[3] Univ Calif San Diego, San Diego, CA 92103 USA
[4] Univ Calif Los Angeles, Los Angeles, CA USA
[5] Royal Hallamshire Hosp, Sheffield S10 2JF, S Yorkshire, England
关键词
lupus; hematopoietic stem cell transplantation;
D O I
10.1038/sj.bmt.1703943
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
At Northwestern University, a phase I/II trial of hematopoietic stem cell transplant (HSCT) for systemic lupus erythematosus (SLE) has shown promising results. A phase III HSCT trial is being developed to confirm efficacy of HSCT vs continuing the currently accepted standard of care, intravenous pulse cyclophosphamide.
引用
收藏
页码:S49 / S51
页数:3
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