An overview of the non-mevalonate pathway for terpenoid biosynthesis in plants

被引：170

作者：

Dubey, VS ^{[1
]}

Bhalla, R

Luthra, R

机构：

[1] Ohio State Univ, Neurobiotechnol Ctr, Columbus, OH 43210 USA

[2] Natl Univ Singapore, Dept Biol Sci, Plant Microbes Interact Lab, Singapore 117604, Singapore

来源：

JOURNAL OF BIOSCIENCES | 2003年 / 28卷 / 05期

关键词：

acetate-mevalonate; DOXP; non-MVA pathway; plants; terpenoids;

D O I：

10.1007/BF02703339

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Terpenoids are known to have many important biological and physiological functions. Some of them are also known for their pharmaceutical significance. In the late nineties after the discovery of a novel non-mevalonate (non-MVA) pathway, the whole concept of terpenoid biosynthesis has changed. In higher plants, the conventional acetate-mevalonate (Ac-MVA) pathway operates mainly in the cytoplasm and mitochondria and synthesizes sterols, sesquiterpenes and ubiquinones predominantly. The plastidic non-MVA pathway however synthesizes hemi-, mono-, sesqui- and di-terpenes, along with carotenoids and phytol chain of chlorophyll. In this paper, recent developments on terpenoids biosynthesis are reviewed with respect to the non-MVA pathway.

引用

页码：637 / 646

页数：10

共 77 条

[1] Biosynthesis of the isoprene units of chamomile sesquiterpenes [J].

Adam, KP ;

Zapp, J .

PHYTOCHEMISTRY, 1998, 48 (06) :953-959

[2] Incorporation of 1-[1-13C]deoxy-D-xylulose in chamomile sesquiterpenes [J].

Adam, KP ;

Thiel, R ;

Zapp, J .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1999, 369 (01) :127-132

[3] Biosynthesis of terpenes:: Studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase [J].

Adam, P ;

Hecht, S ;

Eisenreich, WG ;

Kaiser, J ;

Gräwert, T ;

Arigoni, D ;

Bacher, A ;

Rohdich, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (19) :12108-12113

[4] Temperature-sensitive Arabidopsis mutant defective in 1-deoxy-D-xylulose 5-phosphate synthase within the plastid non-mevalonate pathway of isoprenoid biosynthesis [J].

Araki, N ;

Kusumi, K ;

Masamoto, K ;

Niwa, Y ;

Iba, K .

PHYSIOLOGIA PLANTARUM, 2000, 108 (01) :19-24

[5] Dimethylallyl pyrophosphate is not the committed precursor of isopentenyl pyrophosphate during terpenoid biosynthesis from 1-deoxyxylulose in higher plants [J].

Arigoni, D ;

Eisenreich, W ;

Latzel, C ;

Sagner, S ;

Radykewicz, T ;

Zenk, MH ;

Bacher, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (04) :1309-1314

[6] Terpenoid biosynthesis from 1-deoxy-D-xylulose in higher plants by intramolecular skeletal rearrangement [J].

Arigoni, D ;

Sagner, S ;

Latzel, C ;

Eisenreich, W ;

Bacher, A ;

Zenk, MH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (20) :10600-10605

[7] SOME NEW ASPECTS OF ISOPRENOID BIOSYNTHESIS IN PLANTS - A REVIEW [J].

BACH, TJ .

LIPIDS, 1995, 30 (03) :191-202

[8] Dedicated roles of plastid transketolases during the early onset of isoprenoid biogenesis in pepper fruits [J].

Bouvier, F ;

d'Harlingue, A ;

Suire, C ;

Backhaus, RA ;

Camara, B .

PLANT PHYSIOLOGY, 1998, 117 (04) :1423-1431

[9] Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway [J].

Carretero-Paulet, L ;

Ahumada, I ;

Cunillera, N ;

Rodríguez-Concepción, M ;

Ferrer, A ;

Boronat, A ;

Campos, N .

PLANT PHYSIOLOGY, 2002, 129 (04) :1581-1591

[10] L-Deoxy-D-xylulose 5-phosphate synthase from periwinkle:: cDNA identification and induced gene expression in terpenoid indole alkaloid-producing cells [J].

Chahed, K ;

Oudin, A ;

Guivarc'h, N ;

Hamdi, S ;

Chénieux, JC ;

Rideau, M ;

Clastre, M .

PLANT PHYSIOLOGY AND BIOCHEMISTRY, 2000, 38 (7-8) :559-566

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