Cajal-Retzius cells, Reelin, and the formation of layers

被引:218
作者
Frotscher, M [1 ]
机构
[1] Univ Freiburg, Inst Anat, D-79001 Freiburg, Germany
关键词
D O I
10.1016/S0959-4388(98)80082-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Early-generated Cajal-Retzius cells in the marginal zone of the cortex synthesize and secrete the glycoprotein Reelin. The reelin gene is deleted in reeler mice, which show characteristic alterations in cortical lamination. Recent studies have shed some light on the role of Cajal-Retzius cells and Reelin in the formation of cell and fiber layers in the neocortex and hippocampus.
引用
收藏
页码:570 / 575
页数:6
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