The novel syntheses of α-trifluoromethylated ketones from β-bromoenol phosphates

被引:5
作者
Huang, XG [1 ]
He, YT [1 ]
Ding, YX [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
关键词
trifluoromethylated ketones; beta-bromoenol phosphates;
D O I
10.1080/10426500108040244
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
A series of 1-aryl-3,3,3-trifluro-1-propanones have been synthesized from the reaction of FO2SCF2CO2Me with beta -bromoenol phosphates in the presence of Cul in moderate yield. The reaction mechanism was discussion, the electron-withdrawing substituent at the beta -position of the enol phosphates promoted the catalytic cleavage of the O-P bond in enol phosphates by fluoride ion.
引用
收藏
页码:201 / 207
页数:7
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