Preparation of alkylidenecyclobutanes and their transformation to 2,2-disubstituted cyclopentanones

被引：39

作者：

Fujiwara, T ^{[1
]}

Iwasaki, N ^{[1
]}

Takeda, T ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Dept Appl Chem, Koganei, Tokyo 1848588, Japan

来源：

CHEMISTRY LETTERS | 1998年 / 08期

关键词：

D O I：

10.1246/cl.1998.741

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of ketones with the titanocene reagent prepared by the treatment of 1,1-bis(phenylthio)cyclobutane with the low valent titanium species Cp2Ti[P(OEt)(3)](2) produced the corresponding alkylidenecyclobutanes. These compounds were successfully transformed into 2,2-disubstituted cyclopentanones by the epoxidation and subsequent ring enlargement. The similar reactions of the carbene complexes with carboxylic esters and thiolesters also proceeded to afford (1-alkoxy- and alkylthio-alkylidene)cyclobutanes, respectively, in good yields.

引用

页码：741 / 742

页数：2

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