Advanced pancreatic cancer successfully treated with continuous infusion of 5-fluorouracil and low-dose cisplatin

被引：2

作者：

Kikuchi, H

Ujiie, S

Kanamaru, R

机构：

[1] Miyagi Canc Ctr, Res Inst, Div Pharmacotherapy, Natori, Miyagi 9811293, Japan

[2] Tohoku Univ, Res Inst Dev Aging & Canc, Dept Clin Oncol, Sendai, Miyagi 980, Japan

来源：

INTERNAL MEDICINE | 1998年 / 37卷 / 07期

关键词：

combination chemotherapy; survival time;

D O I：

10.2169/internalmedicine.37.635

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Due to pyloric stenosis in a 59-year-old male with the diagnosis of unresectable pancreatic head cancer, gastro-jejunostomy and cholecysto-jejunostomy were performed. Following the operation, the patient underwent a combination chemotherapy with cisplatin 10 mg/day x 5/week and continuous infusion of 5-fluorouracil 500 mg/day for 4 weeks. After three courses, the tumor size decreased and the serum carcinoembryonic antigen (CEA) level decreased from 89.6 to 4.2 ng/ml without significant adverse effects. During the follow-up, the CEA increased and the patient is now receiving the same treatment, surviving for more than one year.

引用

页码：635 / 637

页数：3