Allergy markers in respiratory epidemiology

被引:48
作者
Baldacci, S
Omenaas, E
Oryszczyn, MP
机构
[1] CNR, Inst Clin Physiol, I-56126 Pisa, Italy
[2] INSERM, U472, Villejuif, France
[3] Univ Bergen, Dept Thorac Med, Bergen, Norway
关键词
atopy; eosinophilia; epidemiology; general population; immunoglobulin E; skin test reactivity;
D O I
10.1183/09031936.01.17407730
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Assessing allergy by measurement of serum immunoglobulin (Ig) E antibodies is fast and safe to perform. Serum antibodies can preferably be assessed in patients with dermatitis and in those who regularly use antihistamines and other pharmacological agents that reduce skin sensitivity. Skin tests represent the easiest tool to obtain quick and reliable information for the diagnosis of respiratory allergic diseases, It is the technique more widely used, specific and reasonably sensitive for most applications as a marker of atopy. Measurement of serum IgE antibodies and skin-prick testing may give complimentary information and can be applied in clinical and epidemiological settings. Peripheral blood eosinophilia is less used, but is important in clinical practice to demonstrate the allergic aetiology of disease, to monitor its clinical course and to address the choice of therapy. In epidemiology, hypereosinophilia seems to reflect an inflammatory reaction in the airways, which may be linked to obstructive airflow limitation.
引用
收藏
页码:773 / 790
页数:18
相关论文
共 154 条
[1]   TOTAL CIRCULATING IGE AND FEV1 IN ADULT MEN - AN EPIDEMIOLOGIC LONGITUDINAL-STUDY [J].
ANNESI, I ;
ORYSZCZYN, MP ;
FRETTE, C ;
NEUKIRCH, F ;
ORVOENFRIJA, E ;
KAUFFMANN, F .
CHEST, 1992, 101 (03) :642-648
[2]  
ANNESI I, 1992, EUR RESPIR J, V5, P1104
[3]   THE EFFECT OF GENETIC AND ENVIRONMENTAL-FACTORS ON THE PREVALENCE OF ALLERGIC DISORDERS AT THE AGE OF 2 YEARS [J].
ARSHAD, SH ;
STEVENS, M ;
HIDE, DW .
CLINICAL AND EXPERIMENTAL ALLERGY, 1993, 23 (06) :504-511
[4]   DISTRIBUTION OF SERUM IGE IN CHILDREN AND ADOLESCENTS AGED 7 TO 16 YEARS IN COPENHAGEN, IN RELATION TO FACTORS OF IMPORTANCE [J].
BACKER, V ;
ULRIK, CS ;
WENDELBOE, D ;
BACHMORTENSEN, N ;
HANSEN, KK ;
LAURESEN, EM ;
DIRKSEN, A .
ALLERGY, 1992, 47 (05) :484-489
[5]   NORMAL VALUES FOR PERIPHERAL-BLOOD WHITE CELL COUNTS IN WOMEN OF 4 DIFFERENT ETHNIC-ORIGINS [J].
BAIN, B ;
SEED, M ;
GODSLAND, I .
JOURNAL OF CLINICAL PATHOLOGY, 1984, 37 (02) :188-193
[6]  
Baldacci S, 1996, ALLERGY, V51, P149, DOI 10.1111/j.1398-9995.1996.tb04579.x
[7]  
BALDACCI S, 1993, EUR RESPIR J, V6, pS624
[8]  
Baldacci Sandra, 1997, Journal of Environmental Pathology Toxicology and Oncology, V16, P77
[9]   IMMEDIATE SKIN-TEST REACTIVITY IN A GENERAL POPULATION SAMPLE [J].
BARBEE, RA ;
LEBOWITZ, MD ;
THOMPSON, HC ;
BURROWS, B .
ANNALS OF INTERNAL MEDICINE, 1976, 84 (02) :129-133
[10]   DISTRIBUTION OF IGE IN A COMMUNITY POPULATION-SAMPLE - CORRELATIONS WITH AGE, SEX, AND ALLERGEN SKIN-TEST REACTIVITY [J].
BARBEE, RA ;
HALONEN, M ;
LEBOWITZ, M ;
BURROWS, B .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1981, 68 (02) :106-111