Enthalpy and entropy in ring closure reactions

被引：36

作者：

Lightstone, FC ^{[1
]}

Bruice, TC ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem, Santa Barbara, CA 93106 USA

来源：

BIOORGANIC CHEMISTRY | 1998年 / 26卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1006/bioo.1998.1096

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The strain and entropy effects of the lactone formation from omega-bromoalkane-carboxylate ions in ring sizes 3 to 23 is reevaluated. We find that Delta H double dagger is the largest contributor to the observed rates (Delta G double dagger) for ring sizes 3 to 6, while -T Delta S double dagger has little influence, -T Delta S double dagger has more effect on the observed rates for ring sizes 8 and larger. (C) 1998 Academic Press.

引用

页码：193 / 199

页数：7

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