The fragility of fertility

被引：42

作者：

Yen, P ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Harbor Res & Educ Inst, Dept Pediat, Torrance, CA 90502 USA

来源：

NATURE GENETICS | 2001年 / 29卷 / 03期

关键词：

D O I：

10.1038/ng1101-243

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Among apparently healthy men who nonetheless produce few or no sperm, about ten percent have microdeletions on their Y chromosome. Most of these de novo mutations occur in the AZFc region on the long arm of the chromosome. The high frequency of deletion is explained by the extraordinary structure of the region, which consists almost entirely of very long repeat units.

引用

页码：243 / 244

页数：2

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