How do thiazide and thiazide-like diuretics lower blood pressure?

被引：65

作者：

Hughes, AD ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci & Technol, Fac Med, NHLI Div, London W2 1NY, England

来源：

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM | 2004年 / 5卷 / 04期

关键词：

thiazides; diuretic; hypertension;

D O I：

10.3317/jraas.2004.034

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Thiazide diuretics are widely used for the treatment of hypertension, but the mechanism by which these drugs lower blood pressure in the long term remains unknown. This article reviews current knowledge about the hypotensive actions of thiazides and thiazide-like diuretics and discusses possible mechanisms of action.

引用

页码：155 / 160

页数：6

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