Urinary tract infection in nephrotic syndrome

被引:23
作者
Gulati, S [1 ]
Kher, V [1 ]
Arora, P [1 ]
Gupta, S [1 ]
Kale, S [1 ]
机构
[1] SANJAY GANDHI POSTGRAD INST MED SCI,DEPT NEPHROL,LUCKNOW 226014,UTTAR PRADESH,INDIA
关键词
nephrotic syndrome; urinary tract infection;
D O I
10.1097/00006454-199603000-00012
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background, The aim was to study the frequency, etiology and predisposing factors of urinary tract infection (UTI) in children with nephrotic syndrome. Methods. A retrospective analysis of all children with nephrotic syndrome was made to determine the occurrence of infectious complications. Results. UTI was found to be the most common infection (40.26%); 49 episodes of culture-positive UTI were observed in 37 children. All 49 episodes occurred in patients who were initially considered to be steroid nonresponders or in relapse. Fourteen of the 49 episodes (28.6%) were asymptomatic. One child had Grade IV reflux and another had a ureteric calculus. The majority of the children had no underlying urinary tract malformations. The children with UTI had significantly lower serum albumin (P < 0.05) and higher serum cholesterol (P < 0.001) concentrations than the group of 206 children without infections. Non-Escherichia coli organisms accounted for 39% of the culture isolates. Conclusions. We believe that UTI is an important but often underdiagnosed infection in children with nephrotic syndrome.
引用
收藏
页码:237 / 240
页数:4
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