Comparison between prospective and retrospective evaluation of Crohn's disease activity index

被引：27

作者：

Frenz, MB ^{[1
]}

Dunckley, P ^{[1
]}

Camporota, L ^{[1
]}

Jewell, DP ^{[1
]}

Travis, SPL ^{[1
]}

机构：

[1] John Radcliffe Hosp, Dept Gastroenterol, Oxford OX3 9DU, England

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2005年 / 100卷 / 05期

关键词：

D O I：

10.1111/j.1572-0241.2005.30487.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The Crohn's disease activity index (CDAI) is the most widely used measure of clinical disease activity in patients entered into clinical trials. The prospective nature of the CDAI calculation precludes its use as a clinical assessment tool. We compared the retrospective evaluation of the CDAI with the prospective evaluation in a heterogenous patient population of 100 patients with Crohn's disease. The correlation between the two assessment methods was good with an r-value of 0.84 (p < 0,0001). There was a tendency of patients with a high retrospective CDAI to have a lower prospective CDAI which is explained by intention to treat. This study shows that a retrospective assisted evaluation of the CDAI is as accurate as the traditional prospective evaluation.

引用

页码：1117 / 1120

页数：4

共 7 条

[1]

BEST WR, 1976, GASTROENTEROLOGY, V70, P439

[2] IOIBD .1. OBSERVER VARIATION IN CALCULATING INDEXES OF SEVERITY AND ACTIVITY IN CROHNS-DISEASE [J].

DEDOMBAL, FT ;

SOFTLEY, A .

GUT, 1987, 28 (04) :474-481

[3] Comparison between prospective and retrospective evaluation of Crohn's disease activity index [J].

Frenz, MB ;

Dunckley, P ;

Camporota, L ;

Jewell, DP ;

Travis, SP .

GASTROENTEROLOGY, 2003, 124 (04) :A193-A193

[4] Does self-administration of a quality of life index for inflammatory bowel disease change the results? [J].

Irvine, EJ ;

Feagan, BG ;

Wong, CJ .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1996, 49 (10) :1177-1185

[5]

NEISSER U, 2000, OXFORD HDB MEMORY, P320

[6] A review of activity indices and efficacy Endpoints for clinical trials of medical therapy in adults with Crohn's disease [J].

Sandborn, WJ ;

Feagan, BG ;

Hanauer, SB ;

Lochs, H ;

Löfberg, R ;

Modigliani, R ;

Present, DH ;

Rutgeerts, P ;

Schölmerich, J ;

Stange, EF ;

Sutherland, LR .

GASTROENTEROLOGY, 2002, 122 (02) :512-530

[7] DEVELOPMENT OF A CROHNS INDEX FOR SURVEY-RESEARCH [J].

SANDLER, RS ;

JORDAN, MC ;

KUPPER, LL .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 1988, 41 (05) :451-458

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