SOCS-1 gene methylation is frequent but does not appear to have prognostic value in patients with multiple myeloma

被引：19

作者：

Depil, S

Saudemont, A

Quesnel, B

机构：

[1] CHU Lille, Serv Malad Sang, F-59037 Lille, France

[2] IRCL, INSERM, U524, Lille, France

来源：

LEUKEMIA | 2003年 / 17卷 / 08期

关键词：

D O I：

10.1038/sj.leu.2403012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1678 / 1679

页数：3

共 6 条

[1]

Baylin SB, 1998, ADV CANCER RES, V72, P141

[2] SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma [J].

Galm, O ;

Yoshikawa, H ;

Esteller, M ;

Osieka, R ;

Herman, JG .

BLOOD, 2003, 101 (07) :2784-2788

[3] Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway [J].

Heinrich, PC ;

Behrmann, I ;

Müller-Newen, G ;

Schaper, F ;

Graeve, L .

BIOCHEMICAL JOURNAL, 1998, 334 :297-314

[4] INTERLEUKIN-6 IN HUMAN MULTIPLE-MYELOMA [J].

KLEIN, B ;

ZHANG, XG ;

LU, ZY ;

BATAILLE, R .

BLOOD, 1995, 85 (04) :863-872

[5] The suppressors of cytokine signaling (SOCS) proteins: Important feedback inhibitors of cytokine action [J].

Nicola, NA ;

Greenhalgh, CJ .

EXPERIMENTAL HEMATOLOGY, 2000, 28 (10) :1105-1112

[6] SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity [J].

Yoshikawa, H ;

Matsubara, K ;

Qian, GS ;

Jackson, P ;

Groopman, JD ;

Manning, JE ;

Harris, CC ;

Herman, JG .

NATURE GENETICS, 2001, 28 (01) :29-35

← 1 →