Are patients with psoriasis undertreated? Results of National Psoriasis Foundation survey

被引:127
作者
Horn, Elizabeth J.
Fox, Kathleen M.
Patel, Vaishali
Chiou, Chiun-Fang
Dann, Frank
Lebwohl, Mark
机构
[1] Natl Psoriasis Fdn, Portland, OR 97223 USA
[2] Strateg Healthcare Solut LLC, Monkton, MD 21111 USA
[3] Amgen Inc, Thousand Oaks, CA USA
[4] Mt Sinai Sch Med, New York, NY USA
关键词
D O I
10.1016/j.jaad.2007.06.042
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
Objective. We sought to assess whether patients with psoriasis with moderate or severe disease are being treated with systemic therapy. Methods. Participants were identified from a random sample of the National Psoriasis Foundation contact database who were 18 years and older, with severe psoriasis (> 10% body surface area) and moderate psoriasis (3%-10% body surface area); respondents with psoriatic arthritis were excluded. Results. In all, 1657 respondents with psoriasis completed the survey (28% severe, 41% moderate). A total of 39% of respondents with severe psoriasis and 37% with moderate psoriasis were not Currently receiving any treatment. Among respondents currently receiving therapy, only 43% of respondents with severe psoriasis received either traditional systemic therapy, biologic therapy, or phototherapy. Limitations: Respondents were from the National Psoriasis Foundation contact database and reported their current severity, which may be affected by their treatment. Body surface area as a measure of patient-reported severity has not been validated but has been used in several published studies. Conclusions: Almost 40% of respondents with psoriasis were currently not receiving treatment. For respondents with severe psoriasis, 26% were treated with systemic therapy, phototherapy, or both; 39% were not in treatment; and 35% were treated with topical therapy alone.
引用
收藏
页码:957 / 962
页数:6
相关论文
共 20 条
[1]
[Anonymous], PSOR STAT
[2]
Therapeutic strategies for psoriasis [J].
Ashcroft, DM ;
Po, ALW ;
Griffiths, CEM .
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2000, 25 (01) :1-10
[3]
AAD consensus statement on psoriasis therapies [J].
Callen, JP ;
Krueger, GG ;
Lebwohl, M ;
McBurney, EI ;
Mease, P ;
Menter, A ;
Paller, AS ;
Pariser, DM ;
Weinblatt, M ;
Zimmerman, G .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2003, 49 (05) :897-899
[4]
Quality of life in patients with psoriasis: A systematic literature review [J].
de Korte, J ;
Sprangers, MAG ;
Mombers, FMC ;
Bos, JD .
JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, 2004, 9 (02) :140-147
[5]
The self-administered psoriasis area and severity index is valid and reliable [J].
Feldman, SR ;
Fleischer, AB ;
Reboussin, DM ;
Rapp, SR ;
Exum, ML ;
Clark, AR ;
Nurre, L .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1996, 106 (01) :183-186
[6]
New topical treatments change the pattern of treatment of psoriasis: dermatologists remain the primary providers of this care [J].
Feldman, SR ;
Fleischer, AB ;
Cooper, JZ .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2000, 39 (01) :41-44
[7]
FINLAY AY, 1995, BRIT J DERMATOL, V132, P236
[8]
Determinants of quality of life in patients with psoriasis: A study from the US population [J].
Gelfand, JM ;
Feldman, SR ;
Stern, RS ;
Thomas, J ;
Rolstad, T ;
Margolis, DJ .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 51 (05) :704-708
[9]
Immunotherapy for psoriasis: from serendipity to selectivity [J].
Griffiths, CEM .
LANCET, 2002, 359 (9303) :279-280
[10]
Psoriasis [J].
Koo, J ;
Lee, E ;
Lee, CS ;
Lebwohl, M .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 50 (04) :613-622