Catalytic and highly efficient 1,4-addition of terminal alkynes to conjugated enones by [RuCl2(p-cymene)]2/pyrrolidine

被引：68

作者：

Chang, S ^{[1
]}

Na, Y

Choi, E

Kim, S

机构：

[1] Ewha Womans Univ, Dept Chem, Seoul 120750, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Chem, Ctr Mol Design & Synth, Taejon 305701, South Korea

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 13期

关键词：

D O I：

10.1021/ol016047m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A wide range of terminal alkynes was added to conjugated enones in a 1,4-fashion by a ruthenium catalyst in the presence of catalytic amounts of an amine base, and the corresponding gamma,delta -alkynyl ketones were obtained in good to excellent yields.

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页码：2089 / 2091

页数：3

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