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The future of PCR technology: Diversification of technologies and applications

被引：17
作者：
White, TJ
机构：
[1] Roche Molecular Systems, Almeda, CA 94501
来源：
TRENDS IN BIOTECHNOLOGY | 1996年 / 14卷 / 12期
关键词：
D O I：
10.1016/S0167-7799(96)10068-8
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The polymerase chain reaction has had a major impact on research in molecular biology, on the human genome project and on the diagnosis of disease. In the future, this powerful technique will be increasingly applied to the study of individual genomic variation and to assess the genetic consequences of ecological and demographic events on past and contemporary populations of many organisms.
引用
收藏
页码：478 / 483
页数：6
相关论文
共 38 条
  • [1] COMPLEMENTARY-DNA SEQUENCING - EXPRESSED SEQUENCE TAGS AND HUMAN GENOME PROJECT
    ADAMS, MD
    KELLEY, JM
    GOCAYNE, JD
    DUBNICK, M
    POLYMEROPOULOS, MH
    XIAO, H
    MERRIL, CR
    WU, A
    OLDE, B
    MORENO, RF
    KERLAVAGE, AR
    MCCOMBIE, WR
    VENTER, JC
    [J]. SCIENCE, 1991, 252 (5013) : 1651 - 1656
  • [2] Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: Activation of the vertebrate homologue of the Drosophila seven in absentia gene
    Amson, RB
    Nemani, M
    Roperch, JP
    Israeli, D
    Bougueleret, L
    LeGall, I
    Medhioub, M
    LinaresCruz, G
    Lethrosne, F
    Pasturaud, P
    Piouffre, L
    Prieur, S
    Susini, L
    Alvaro, V
    Millasseau, P
    Guidicelli, C
    Bui, H
    Massart, C
    Cazes, L
    Dufour, F
    BruzzoniGiovanelli, H
    Owadi, H
    Hennion, C
    Charpak, G
    Dausset, J
    Calvo, F
    Oren, M
    Cohen, D
    Telerman, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (09) : 3953 - 3957
  • [3] [Anonymous], 1994, POLYMERASE CHAIN REA
  • [4] PCR ANALYSIS OF DNA-SEQUENCES IN SINGLE CELLS - SINGLE SPERM GENE-MAPPING AND GENETIC-DISEASE DIAGNOSIS
    ARNHEIM, N
    LI, HH
    CUI, XF
    [J]. GENOMICS, 1990, 8 (03) : 415 - 419
  • [5] BURKE T, 1991, GENES ECOLOGY, P229
  • [6] Molecular markers reveal cryptic sex in the human pathogen Coccidioides immitis
    Burt, A
    Carter, DA
    Koenig, GL
    White, TJ
    Taylor, JW
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (02) : 770 - 773
  • [7] Erlich H.A., 1989, PCR TECHNOLOGY PRINC
  • [8] REALIZED REPRODUCTIVE SUCCESS OF POLYGYNOUS RED-WINGED BLACKBIRDS REVEALED BY DNA MARKERS
    GIBBS, HL
    WEATHERHEAD, PJ
    BOAG, PT
    WHITE, BN
    TABAK, LM
    HOYSAK, DJ
    [J]. SCIENCE, 1990, 250 (4986) : 1394 - 1397
  • [9] MOLECULAR-GENETIC ANALYSES OF THE TYROLEAN ICE MAN
    HANDT, O
    RICHARDS, M
    TROMMSDORFF, M
    KILGER, C
    SIMANAINEN, J
    GEORGIEV, O
    BAUER, K
    STONE, A
    HEDGES, R
    SCHAFFNER, W
    UTERMANN, G
    SYKES, B
    PAABO, S
    [J]. SCIENCE, 1994, 264 (5166) : 1775 - 1778
  • [10] Correlation between male song repertoire, extra-pair paternity and offspring survival in the great reed warbler
    Hasselquist, D
    Bensch, S
    vonSchantz, T
    [J]. NATURE, 1996, 381 (6579) : 229 - 232
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