A review on the effects of ionizing radiation on blood and blood components

被引:38
作者
Jacobs, GP [1 ]
机构
[1] Dr Geoffrey P Jacobs Associates, IL-91162 Jerusalem, Israel
来源
RADIATION PHYSICS AND CHEMISTRY | 1998年 / 53卷 / 05期
关键词
D O I
10.1016/S0969-806X(98)00185-6
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The major application of blood irradiation is for the prevention of graft-versus-host disease on immunodeficient patients by the abrogation of T-lymphocytes. Despite screening of blood donations, transfusion associated transmission of infections due to contaminated blood products is common. Hence, there is potential for the application of irradiation for the inactivation of pathogenic microbes in blood products. Literature on the effect of radiation on blood components is reviewed in order to make a rational decision on the feasibility of their irradiation. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:511 / 523
页数:13
相关论文
共 140 条
[1]   THE HUMAN-LYMPHOCYTE MICRONUCLEUS ASSAY - RESPONSE OF CORD BLOOD-LYMPHOCYTES TO BETA-IRRADIATION AND BLEOMYCIN [J].
AGHAMOHAMMADI, SZ ;
HENDERSON, L ;
COLE, RJ .
MUTATION RESEARCH, 1984, 130 (06) :395-401
[2]   IRRADIATION OF PROTEINS IN THE SOLID STATE .1. AGGREGATION AND DISORGANIZATION OF SECONDARY STRUCTURE IN BOVINE SERUM ALBUMIN [J].
ALEXANDER, P ;
HAMILTON, LDG ;
STACEY, KA .
RADIATION RESEARCH, 1960, 12 (05) :510-525
[3]   COMPARISON OF SOME DIRECT AND INDIRECT EFFECTS OF IONIZING RADIATIONS IN PROTEIN [J].
ALEXANDER, P ;
FOX, M ;
STACEY, KA ;
ROSEN, D .
NATURE, 1956, 178 (4538) :846-849
[4]  
*AM ASS BLOOD BANK, 1996, STAND BLOOD BANKS TR
[5]  
ANDERSON G, 1972, IRRADIATION BLOOD CO, P63
[6]  
ANDERSON KC, 1991, BLOOD, V77, P2096
[7]  
Anderson KC, 1992, IRRADIATION BLOOD CO, P31
[8]  
[Anonymous], RAD RES
[9]  
[Anonymous], 1991, STAND BLOOD BANKS TR
[10]  
[Anonymous], 1995, US PHARM, P2053